UO Poisoning Skill Guide
Poisoning lets you apply poison to weapons or food and increases the potency of poison delivered by certain specials (e.g., Infectious Strike). It’s popular for PvP dexxers and stealth builds and pairs well with fast weapons and Fencing.
Poisoning is a combat skill in Ultima Online, rated as Medium difficulty to train. This guide walks you through everything you need to raise Poisoning from 0 to grandmaster, including the most efficient training methods, the targets and items to use at each skill range, and the gains you can expect along the way. Whether you are building your first character or optimizing a finished template, the breakdown below will help you train Poisoning as quickly and cheaply as possible.
Below you will find an overview of what Poisoning does, a step-by-step training guide, recommended skill ranges, any bonuses Poisoning provides, and the templates that pair well with it. If you would rather skip the grind, UO King can deliver a ready-made character or the gear you need to support a Poisoning build on your shard.
| Skill Range | Recommended Method | Notes |
|---|---|---|
| 0.0 – 30.0 | Train from Assassin/Thief NPC | Buy up to 30 if available |
| 30.0 – 55.0 | Apply Lesser Poison to daggers/food | High success; fast gains |
| 55.0 – 75.0 | Apply Regular Poison | Switch targets after charges are used |
| 75.0 – 90.0 | Apply Greater Poison | Keep stacks of empty food/cheap weapons |
| 90.0 – 100.0 | Apply Deadly Poison | Success improves with Anatomy/DEX for survival if training near mobs |
| 100.0 – 120.0 | Deadly/Lethal on higher-difficulty items | Shard rules vary for Lethal application |